SCHEMBL4805384

SCHEMBL4805384

OCC1(CO)COC2(CCCCC2)N1

nearest known ligand 0.96

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.96
ALDH1A1 P00352 1/20 0.96
MAPT P10636 1/20 0.96
PKM P14618 1/20 0.62
POLB P06746 1/20 0.59
GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12858833 0.98 KDM4E (1.00) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL29564993 0.89 KDM4E (0.83) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL9145815 0.89 KDM4E (0.76) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL6550349 0.86 KDM4E (0.71) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL30530607 0.78 KDM4E (0.66) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL534610 0.76 KDM4E (0.58) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL9778876 0.75 KDM4E (0.56) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL7118211 0.69 KDM4E (0.48) KDM4EALDH1A1MAPT
SCHEMBL9873656 0.67 KDM4E (0.47) KDM4EALDH1A1MAPTPKMPOLB
SCHEMBL3886463 0.67 KDM4E (0.47) KDM4EALDH1A1MAPTPKMPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383832-A1 STABILIZED CANDLE WAX Ciba SC Holding AG (CH) 2004-01-28 EP claimed
US-6540795-B2 Stabilized against discoloration and fading CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-01 US claimed
US-20030000128-A1 Candle wax stabilized with oxazolidines CIBA SPECIALTY CHEMICALS CORP. 2003-01-02 US claimed
WO-2002079313-A1 STABILIZED CANDLE WAX CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO claimed
EP-0946689-A4 ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS EXXON RESEARCH ENGINEERING CO (US) 2000-11-22 EP claimed
EP-0946689-A1 ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1999-10-06 EP claimed
CN-1230211-A Antioxidant and antioxidant co-promoter capable of generating hydroperoxyl radicals EXXON RESEARCH ENGINEERING CO (US) 1999-09-29 CN claimed
WO-1998011181-A1 ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-03-19 WO claimed
US-4125518-A 1-Oxa-4-azaspiro[4,5]decanes as light stabilizers for polymers AMERICAN CYANAMID COMPANY (US) 1978-11-14 US claimed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
US-7339003-B2 Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-03-04 US disclosed
WO-2007134449-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2007-11-29 WO disclosed
US-20050145831-A1 Antioxidants and antioxidant boosters capable of producing hydroperoxyl radicals ALDRICH HAVEN S (US) 2005-07-07 US disclosed
EP-0946689-A4 ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS EXXON RESEARCH ENGINEERING CO (US) 2000-11-22 EP disclosed
EP-0946689-A1 ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1999-10-06 EP disclosed
CN-1230211-A Antioxidant and antioxidant co-promoter capable of generating hydroperoxyl radicals EXXON RESEARCH ENGINEERING CO (US) 1999-09-29 CN disclosed
WO-1998011181-A1 ANTIOXIDANTS AND ANTIOXIDANT BOOSTERS CAPABLE OF PRODUCING HYDROPEROXYL RADICALS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1998-03-19 WO disclosed
US-4999369-A Antitumor agents BURROUGHS WELLCOME CO. (US) 1991-03-12 US disclosed
US-4125518-A 1-Oxa-4-azaspiro[4,5]decanes as light stabilizers for polymers AMERICAN CYANAMID COMPANY (US) 1978-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS APP, BACE1, IAPP KDM4E 4738/4885ALDH1A1 4135/4885MAPT 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.