SCHEMBL4806052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4802343	0.91	TEK (0.83)	TEKFLT1KDRMAPK14KIT
	SCHEMBL4800818	0.89	TEK (0.79)	TEKFLT1KDRMAPK14KDM4E
	SCHEMBL4796404	0.89	TEK (0.79)	TEKFLT1KDRMAPK14KIT
	SCHEMBL4797768	0.89	TEK (0.79)	TEKFLT1KDRMAPK14MAP4K4
	SCHEMBL4803000	0.89	TEK (0.79)	TEKFLT1KDRMAPK14FGFR1
	SCHEMBL4802939	0.88	TEK (1.00)	TEKFLT1KDRKDM4EALDH1A1
	SCHEMBL4798793	0.88	TEK (0.78)	TEKFLT1KDRMAP4K4FGFR1
	SCHEMBL4802728	0.87	TEK (0.76)	TEKFLT1KDRMAP4K4KDM2B
	SCHEMBL4803081	0.86	TEK (0.65)	TEKFLT1KDRMAPK14MAP4K4
	SCHEMBL4801246	0.84	TEK (0.57)	TEKFLT1KDRMAPK14NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.