Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4325200 | 0.86 | KMT2A (0.52) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL13909331 | 0.85 | CREBBP (0.46) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL3811958 | 0.83 | KMT2A (0.64) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL3809200 | 0.82 | KMT2A (0.48) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL2830732 | 0.82 | ICAM1 (0.53) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL393604 | 0.80 | MEN1 (0.44) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL12141797 | 0.80 | ICAM1 (0.42) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL32681294 | 0.80 | HDAC1 (0.49) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL25231400 | 0.79 | MEN1 (0.44) | MEN1KMT2ACREBBPICAM1SELE | |
| SCHEMBL10007917 | 0.79 | ICAM1 (0.45) | MEN1KMT2ACREBBPICAM1SELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077646-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | WO | disclosed |