⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806296 | 0.94 | KMT2A (0.40) | — | |
| SCHEMBL11131196 | 0.85 | KMT2A (0.50) | — | |
| SCHEMBL6283056 | 0.82 | — | — | |
| SCHEMBL8078444 | 0.78 | KMT2A (0.50) | — | |
| SCHEMBL3498191 | 0.74 | — | — | |
| SCHEMBL9634269 | 0.74 | — | — | |
| SCHEMBL27816066 | 0.72 | POLB (0.41) | — | |
| SCHEMBL10885356 | 0.72 | — | — | |
| SCHEMBL43730 | 0.72 | — | — | |
| SCHEMBL1276454 | 0.71 | KMT2A (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440700-A | The method for being used to prepare the copolymer of ethylene | 维尔萨利斯股份公司 | 2018-08-24 | — | — | CN | claimed |
| CN-118355029-A | Methods of treating diffuse large B-cell lymphomas using anti-CD 79B immunoconjugates | 基因泰克公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112689634-B | SMAD3 inhibitors | 莫扎制药有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118302198-A | Conjugates comprising phosphorus (V) and a camptothecin moiety | TUBULIS 股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118302197-A | Conjugates comprising phosphorus (V) and a drug moiety | TUBULIS 股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113677364-B | Pharmaceutical compositions comprising anti-191P 4D12 antibody drug conjugates and methods of use thereof | 艾更斯司股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-111569086-B | Methylene carbamate linkers for use with target-drug conjugates | 西雅图基因公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-111558049-B | Methylene carbamate linkers for use with target-drug conjugates | 西雅图基因公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118201946-A | Lipidated polymyxin analogues | 奥克兰联合服务有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-20240190958-A1 | NOVEL ANTIBODY DRUG CONJUGATES WITH NOVEL NAPI2B ANTIBODIES, THERAPEUTIC METHODS AND USES THEREOF | TUBULIS GMBH (DE) | 2024-06-13 | — | — | US | disclosed |
| WO-2018197963-A1 | METHOD OF CYCLIC COMPOUNDS PRODUCTION IN OLEFINE METATHESIS REACTION AND USE OF RUTHENIUM CATALYSTS IN PRODUCTION OF CYCLIC OLEFINS IN OLEFINE METATHESIS REACTION | UNIWERSYTET WARSZAWSKI (PL) | 2018-11-01 | — | — | WO | disclosed |
| CN-108473707-A | Foamed resin molded article and method for producing same | 丰田纺织株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-108440700-A | The method for being used to prepare the copolymer of ethylene | 维尔萨利斯股份公司 | 2018-08-24 | — | — | CN | disclosed |
| WO-2018100515-A1 | NOVEL RUTHENIUM COMPLEX, METHOD OF ITS PRODUCTION AND ITS USE IN REACTION OF OLEFINE METATHESIS | UNIWERSYTET WARSZAWSKI (PL) | 2018-06-07 | — | — | WO | disclosed |
| US-7342017-B2 | 1,2,5-Thiadiazol-3-yl-piperazine therapeutic agents useful for treating pain, depression and anxiety | EURO-CELTIQUE S.A. (LU) | 2008-03-11 | — | — | US | disclosed |
| EP-1487829-B1 | THIADIAZOLYLPIPERAZINE DERIVATIVES USEFUL FOR TREATING OR PREVENTING PAIN | EURO CELTIQUE SA (LU) | 2007-10-10 | — | — | EP | disclosed |
| US-20060074090-A1 | 1,2,5-Thiadiazol-3-yl-piperazine therapeutic agents useful for treating pain, depression and anxiety | EURO-CELTIQUE S.A. | 2006-04-06 | — | — | US | disclosed |
| EP-1487829-A1 | THIADIAZOLYLPIPERAZINE DERIVATIVES USEFUL FOR TREATING OR PREVENTING PAIN | Euro-Celtique S.A. (LU) | 2004-12-22 | — | — | EP | disclosed |
| US-20040006091-A1 | Therapeutic agents useful for treating or preventing pain | PURDUE PHARMA L.P. | 2004-01-08 | — | — | US | disclosed |
| WO-2003074520-A1 | THIADIAZOLYLPIPERAZINE DERIVATIVES USEFUL FOR TREATING OR PREVENTING PAIN | EURO-CELTIQUE, S.A. (LU) | 2003-09-12 | — | — | WO | disclosed |