SCHEMBL4807580

SCHEMBL4807580

CCOC(=O)CCCCC(=O)CC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
ALDH1A1 P00352 3/20 0.49
ALOX15 P16050 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
DGKA P23743 1/20 0.48
GAA P10253 2/20 0.48
MGAM O43451 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
NR1I2 O75469 1/20 0.47
PGR P06401 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
PTGS2 P35354 1/20 0.47
PDE4D Q08499 1/20 0.47
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6253597 0.98 CYP1A2 (0.57) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL3947515 0.95 CYP1A2 (0.59) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL25616349 0.88 CYP1A2 (0.61) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL4382341 0.88 CYP1A2 (0.61) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL11356300 0.88 CYP1A2 (0.61) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL8570508 0.88 CYP1A2 (0.73) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL50610 0.88 CYP1A2 (0.73) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL6413180 0.86 CYP1A2 (0.64) CYP1A2ALDH1A1ALOX15TDP1CYP3A4
SCHEMBL135579 0.86 GAA (0.52) CYP1A2ALDH1A1ALOX15TDP1TSHR
SCHEMBL33870 0.85 CYP1A2 (0.70) CYP1A2ALDH1A1ALOX15TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-217450115-U Production system of 8-chloro-6-oxo-ethyl octanoate 上海橡实化学有限公司 2022-09-20 CN disclosed
CN-217450115-U Production system of 8-chloro-6-oxo-ethyl octanoate 上海橡实化学有限公司 2022-09-20 CN disclosed
WO-2008087611-A2 PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2008-07-24 WO disclosed