Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571213 | 1.00 | RXFP1 (0.40) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL3155804 | 0.93 | RXFP1 (0.40) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL3143809 | 0.92 | RXFP1 (0.42) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2573629 | 0.91 | RXFP1 (0.49) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL3161556 | 0.91 | KDM4E (0.41) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2570006 | 0.90 | RXFP1 (0.41) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2571162 | 0.90 | MAPT (0.41) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2568537 | 0.89 | KMT2A (0.43) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL3157321 | 0.89 | RXFP1 (0.40) | RXFP1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL2568413 | 0.87 | RXFP1 (0.44) | RXFP1SMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |