Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.68 |
| ▸ | ITGA5 | P08648 | 20/20 | 0.68 |
| ▸ | ITGB3 | P05106 | 13/20 | 0.68 |
| ▸ | ITGAV | P06756 | 13/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199496 | 0.91 | ITGB1 (0.82) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4207626 | 0.81 | ITGB1 (1.00) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4069515 | 0.78 | ITGB1 (1.00) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4196184 | 0.78 | ITGAV (0.65) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4929776 | 0.77 | ITGB1 (0.84) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4069250 | 0.76 | ITGB1 (0.77) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4069363 | 0.75 | ITGB1 (0.89) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4250019 | 0.74 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4197881 | 0.72 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL4066343 | 0.70 | ITGB1 (0.72) | ITGB1ITGA5ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093065-A1 | L-ALANINE DERIVATIVES AS α5βL ANTAGONISTS | ASTRAZENECA AB (SE) | 2008-08-07 | — | — | WO | disclosed |