Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888701 | 0.98 | AVPR1B (0.84) | AVPR1BCYP3A4 | |
| SCHEMBL2891181 | 0.94 | AVPR1B (0.85) | AVPR1BCYP3A4 | |
| SCHEMBL2885968 | 0.92 | AVPR1B (0.89) | AVPR1BCYP3A4 | |
| SCHEMBL2889118 | 0.91 | AVPR1B (0.77) | AVPR1BCYP3A4 | |
| SCHEMBL2893866 | 0.90 | AVPR1B (0.71) | AVPR1BCYP3A4 | |
| SCHEMBL2891139 | 0.90 | AVPR1B (1.00) | AVPR1BCYP3A4 | |
| SCHEMBL2889280 | 0.90 | AVPR1B (0.70) | AVPR1BCYP3A4 | |
| SCHEMBL2885220 | 0.88 | AVPR1B (0.91) | AVPR1BCYP3A4 | |
| SCHEMBL4081698 | 0.88 | AVPR1B (0.92) | AVPR1BCYP3A4 | |
| SCHEMBL2892855 | 0.87 | AVPR1B (0.96) | AVPR1BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486931-B2 | Substituted oxindole compounds | ABBOTT GMBH & CO. KG (DE) | 2013-07-16 | — | — | US | claimed |
| US-8486931-B2 | Substituted oxindole compounds | ABBOTT GMBH & CO. KG (DE) | 2013-07-16 | — | — | US | disclosed |
| WO-2008107399-A1 | SUBSTITUTED OXINDOLE COMPOUNDS | ABBOTT GMBH & CO. KG (DE) | 2008-09-12 | — | — | WO | disclosed |