Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.60 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808602 | 0.90 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL4807959 | 0.90 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL4807874 | 0.87 | CNR1 (0.47) | CNR1ALDH1A1CYP1A2USP2LMNA | |
| SCHEMBL4806724 | 0.86 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL4807904 | 0.86 | CNR1 (0.49) | CNR1CNR2ALDH1A1CYP1A2USP2 | |
| SCHEMBL14107189 | 0.83 | CNR1 (0.49) | CNR1CNR2ALDH1A1CYP1A2USP2 | |
| SCHEMBL4807899 | 0.83 | CNR1 (0.47) | CNR1CNR2ALDH1A1CYP1A2USP2 | |
| SCHEMBL4809154 | 0.83 | CNR1 (0.45) | CNR1CNR2ALDH1A1CYP1A2USP2 | |
| SCHEMBL4806722 | 0.83 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL4807802 | 0.83 | CNR1 (0.55) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405221-B2 | Substituted pyrimidines | MERCK & CO., INC. (US) | 2008-07-29 | — | — | US | disclosed |