Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 14/20 | 0.48 |
| ▸ | CA12 | O43570 | 13/20 | 0.48 |
| ▸ | CA1 | P00915 | 13/20 | 0.48 |
| ▸ | CA4 | P22748 | 11/20 | 0.48 |
| ▸ | CA5A | P35218 | 11/20 | 0.48 |
| ▸ | CA7 | P43166 | 11/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 11/20 | 0.48 |
| ▸ | CA9 | Q16790 | 7/20 | 0.48 |
| ▸ | CA6 | P23280 | 4/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.45 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15269920 | 0.89 | TSHR (0.52) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL15269916 | 0.89 | TSHR (0.52) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL18466634 | 0.89 | TSHR (0.67) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL12601659 | 0.87 | TSHR (0.64) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL12334423 | 0.87 | TSHR (0.64) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL15368881 | 0.87 | TSHR (0.64) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL12649999 | 0.87 | TSHR (0.64) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL2469148 | 0.87 | TSHR (0.64) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL222652 | 0.87 | TSHR (0.64) | TSHRPTPN1CA2CA12CA1 | |
| SCHEMBL2865475 | 0.86 | TSHR (0.63) | TSHRPTPN1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417032-B2 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417032-B2 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417032-B2 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-26 | — | — | US | disclosed |
| US-20060035841-A1 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-16 | — | — | US | disclosed |
| US-20060025349-A1 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035841-A1 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | SLC5A1, SLC5A2, SLC2A1 | TSHR 3664/4885PTPN1 127/4885CA2 838/4885 |
| US-20060025349-A1 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | SLC5A1, SLC5A2, SLC2A1 | TSHR 3665/4885PTPN1 180/4885CA2 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.