Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 17/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042818 | 1.00 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL4811240 | 1.00 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL4788813 | 0.99 | CHRM1 (0.66) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL4814480 | 0.99 | CHRM1 (0.66) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL4788805 | 0.99 | CHRM1 (0.66) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL600432 | 0.91 | CHRM1 (0.73) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL601395 | 0.91 | CHRM1 (0.73) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL600431 | 0.91 | CHRM1 (0.73) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL602470 | 0.90 | CHRM1 (0.72) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL602328 | 0.90 | CHRM1 (0.72) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | claimed |
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |