⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107295 | 0.93 | — | — | |
| SCHEMBL4816147 | 0.90 | — | — | |
| SCHEMBL4813316 | 0.90 | — | — | |
| SCHEMBL25112407 | 0.68 | — | — | |
| SCHEMBL25032719 | 0.66 | TDP1 (0.31) | — | |
| SCHEMBL25107222 | 0.66 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL11569257 | 0.62 | — | — | |
| SCHEMBL4814678 | 0.60 | — | — | |
| SCHEMBL24752509 | 0.55 | — | — | |
| SCHEMBL779764 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650216-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE DIMER OF PHOSPHORUS HETEROCYCLE | NIPPON CHEMICAL IND COMPANY LTD (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-7411096-B2 | Process for producing optically active phosphorus heterocyclic dimer | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20060211888-A1 | 2,2'-bis-(1-alkylphosphetanes); a primary alkyl or cycloalkyl phosphine is reacted with 1,3-dichloropropane, in the presence of n-butyllithium, and then reacted with boron trihydride, oxygen, or sulfur, dimerizing, removing the boron trihydride, oxygen, or sulfur; assymetric hydrogenation catalysts | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2006-09-21 | — | — | US | disclosed |
| US-20060189818-A1 | Novel optically active phosphorus-chiral diphosphetanes, intermediates of the same, and transition metal complexes containing the diphosphetanes as the ligand | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1650217-A1 | NOVEL OPTICALLY ACTIVE PHOSPHORUS-CHIRAL DIPHOSPHETANES, INTERMEDIATES OF THE SAME, AND TRANSITION METAL COMPLEXES CONTAINING THE DIPHOSPHETANES AS THE LIGAND | Nippon Chemical Industrial Co., Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |
| EP-1650216-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE DIMER OF PHOSPHORUS HETEROCYCLE | NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED (JP) | 2006-04-26 | — | — | EP | disclosed |