Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813053 | 1.00 | CHEK1 (0.77) | CHEK1PDGFRB | |
| SCHEMBL4813614 | 0.91 | CHEK1 (0.76) | CHEK1PDGFRB | |
| SCHEMBL4815267 | 0.91 | CHEK1 (0.83) | CHEK1PDGFRB | |
| SCHEMBL4813313 | 0.90 | CHEK1 (0.84) | CHEK1PDGFRB | |
| SCHEMBL4816895 | 0.89 | PDGFRB (0.74) | CHEK1PDGFRB | |
| SCHEMBL4809966 | 0.88 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL4813750 | 0.83 | CHEK1 (0.81) | CHEK1PDGFRB | |
| SCHEMBL6789032 | 0.82 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL6790169 | 0.82 | CHEK1 (1.00) | CHEK1 | |
| SCHEMBL6215320 | 0.81 | CHEK1 (1.00) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320986-B2 | Fused tri and tetra-cyclic pyrazole kinase inhibitors | ABBOTT LABORTORIES (US) | 2008-01-22 | — | — | US | disclosed |