⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812534 | 1.00 | — | — | |
| SCHEMBL4814120 | 1.00 | — | — | |
| SCHEMBL4814102 | 0.86 | — | — | |
| SCHEMBL4815493 | 0.86 | — | — | |
| SCHEMBL4817426 | 0.81 | DYRK1A (0.46) | — | |
| SCHEMBL14268170 | 0.81 | DYRK1A (0.46) | — | |
| SCHEMBL4816923 | 0.80 | GSK3A (0.36) | — | |
| SCHEMBL4814061 | 0.80 | GSK3A (0.36) | — | |
| SCHEMBL4814042 | 0.80 | GSK3A (0.36) | — | |
| SCHEMBL3881489 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335672-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7335672-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7335672-B2 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-20060058308-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2006-03-16 | — | — | US | disclosed |