Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778845 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14778884 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14778504 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14779155 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14779694 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14779154 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14778437 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14778885 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14779452 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS | |
| SCHEMBL14779834 | 0.85 | TSHR (0.38) | THRBTSHRGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |