Tert-Butylbenzene

Tert-Butylbenzene

SCHEMBL4814841

CC(C)(C)c1ccccc1.c1ccc(C2CCCCC2)cc1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 6/20 0.49
SIGMAR1 Q99720 2/20 0.44
CYP11B2 P19099 1/20 0.43
KIF11 P52732 1/20 0.43
CYP2D6 P10635 3/20 0.42
TRPA1 O75762 1/20 0.42
KMO O15229 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALDH1A1 P00352 1/20 0.40
APEX1 P27695 1/20 0.40
BLM P54132 1/20 0.40
DRD2 P14416 1/20 0.40
DRD1 P21728 1/20 0.40
DRD4 P21917 1/20 0.40
DRD5 P21918 1/20 0.40
DRD3 P35462 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6902989 0.86 SLC6A2 (0.49) TSHRCYP2C9ALDH1A1
SCHEMBL4329015 0.86 SLC6A2 (0.49) TSHRCYP2C9ALDH1A1
SCHEMBL5146562 0.84 SLC6A2 (0.46) TSHRCYP2C9ALDH1A1
SCHEMBL11562787 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1
SCHEMBL19198566 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1
SCHEMBL790829 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1
SCHEMBL19262690 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1
SCHEMBL42833 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1
SCHEMBL447032 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1
SCHEMBL30731352 0.83 SLC18A3 (0.63) SLC18A3SIGMAR1CYP11B2CYP2D6TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393956-B2 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides BASF AKTIENGESELLSCHAFT (DE) 2008-07-01 US claimed