Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049799 | 1.00 | MAPT (0.30) | MAPT | |
| SCHEMBL7638599 | 0.94 | — | — | |
| SCHEMBL7637193 | 0.94 | — | — | |
| SCHEMBL7640093 | 0.94 | — | — | |
| SCHEMBL1052042 | 0.94 | KDM1A (0.31) | — | |
| SCHEMBL7637190 | 0.94 | — | — | |
| SCHEMBL7640090 | 0.94 | — | — | |
| SCHEMBL1052040 | 0.94 | KDM1A (0.31) | — | |
| SCHEMBL6015270 | 0.94 | KDM1A (0.31) | — | |
| SCHEMBL7638595 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215676-A | Specific conjugation of antibody drug conjugates | 杭州多禧生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-117980327-A | Specific coupling of antibodies | 杭州多禧生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-110023334-B | anti-GP 73 antibodies and immunoconjugates | 科雅博有限责任公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116940586-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116940585-A | Compounds comprising fibroblast activation protein ligands and uses thereof | 3B制药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116063515-A | anti-FCRH 5 antibodies | 基因泰克公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115443134-A | Conjugates of cell binding molecules and camptothecin analogs | 杭州多禧生物科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| EP-3997104-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2022-05-18 | — | — | EP | disclosed |
| CN-114206340-A | Methods of treating follicular lymphoma using anti-CD 79B immunoconjugates | 豪夫迈·罗氏有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-112272669-A | Cross-linked pyrrolobenzodiazepine dimer (PBD) derivatives and conjugates thereof | 杭州多禧生物科技有限公司 | 2021-01-26 | — | — | CN | disclosed |
| WO-2021005131-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2021-01-14 | — | — | WO | disclosed |
| CN-111093707-A | Tubulysin homolog conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-110621673-A | Double-stranded linked cytotoxic drug conjugates | 杭州多禧生物科技有限公司 | 2019-12-27 | — | — | CN | disclosed |
| EP-3505191-A1 | AURISTATINS HAVING AN AMINOBENZOIC ACID UNIT AT THE N TERMINUS | Seattle Genetics, Inc. (US) | 2019-07-03 | — | — | EP | disclosed |
| EP-1817336-B1 | AURISTATINS HAVING AN AMINOBENZOIC ACID UNIT AT THE N TERMINUS | SEATTLE GENETICS INC (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-2844300-B1 | ANTI-PMEL17 ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH INC (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-3046940-A1 | METHODS OF USING ANTI-LGR5 ANTIBODIES | F. Hoffmann-La Roche AG (CH) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015042108-A1 | METHODS OF USING ANTI-LGR5 ANTIBODIES | GENENTECH, INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| EP-2078016-B1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2012-02-01 | — | — | EP | disclosed |