Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.42 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL482102 | 0.83 | MTOR (0.51) | MTORPIK3CAGSK3AMAP3K11 | |
| Hydrochloric Acid SCHEMBL481472 | 0.80 | MTOR (0.73) | MTORPIK3CAGSK3A | |
| SCHEMBL481880 | 0.80 | MTOR (0.72) | MTORPIK3CAGSK3ARICTORRPTOR | |
| SCHEMBL482112 | 0.78 | MTOR (0.68) | MTORPIK3CAGSK3ARICTORRPTOR | |
| Hydrochloric Acid SCHEMBL27790997 | 0.73 | MTOR (0.70) | MTORPIK3CAGSK3A | |
| SCHEMBL27790998 | 0.67 | MTOR (0.83) | MTORPIK3CAGSK3AMAP3K11 | |
| SCHEMBL481629 | 0.67 | MTOR (0.84) | MTORPIK3CAGSK3AMAP3K11 | |
| SCHEMBL481548 | 0.66 | MTOR (0.63) | MTORPIK3CAMAP3K11RICTORRPTOR | |
| SCHEMBL481800 | 0.65 | MTOR (0.80) | MTORPIK3CAGSK3AMAP3K11 | |
| SCHEMBL2206999 | 0.65 | MTOR (1.00) | MTORPIK3CAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078016-B1 | HETEROARYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2012-02-01 | — | — | EP | disclosed |