⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146874 | 0.92 | — | — | |
| SCHEMBL11148134 | 0.86 | — | — | |
| SCHEMBL11147508 | 0.80 | — | — | |
| SCHEMBL11145876 | 0.80 | — | — | |
| SCHEMBL11151868 | 0.80 | — | — | |
| SCHEMBL11150208 | 0.77 | — | — | |
| SCHEMBL11148339 | 0.75 | PREP (0.31) | — | |
| SCHEMBL11148425 | 0.75 | — | — | |
| SCHEMBL11145669 | 0.75 | MAPT (0.41) | — | |
| SCHEMBL9660872 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222081-A1 | Cross-linked hyaluronate compounds | GIANOLIO DIEGO A | 2005-10-06 | — | — | US | claimed |
| US-7387836-B2 | Aziridine compounds and their use in medical devices | GENZYME CORPORATION (US) | 2008-06-17 | — | — | US | disclosed |
| US-20050249953-A1 | Aziridine compounds and their use in medical devices | GIANOLIO DIEGO A | 2005-11-10 | — | — | US | disclosed |
| US-20050222081-A1 | Cross-linked hyaluronate compounds | GIANOLIO DIEGO A | 2005-10-06 | — | — | US | disclosed |