Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL4816588

OCCCCCCCCO.OCCOCCO

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.71
MAPK1 P28482 2/20 0.71
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
THRB P10828 1/20 0.55
HTT P42858 1/20 0.55
MAPT P10636 1/20 0.55
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.43
LMNA P02545 3/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.37
GPR84 Q9NQS5 1/20 0.36
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
USP2 O75604 1/20 0.34
CYP3A4 P08684 1/20 0.34
CASP1 P29466 1/20 0.34
SLCO1B3 Q9NPD5 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL270712 1.00 TSHR (0.71) TSHRMAPK1MEN1KMT2ATHRB
1,5-Pentanediol SCHEMBL11430206 1.00 TSHR (0.71) TSHRMAPK1MEN1KMT2ATHRB
Tetraethylene Glycol SCHEMBL2540124 0.97 MEN1 (0.73) TSHRMAPK1MEN1KMT2ATHRB
Triethylene Glycol SCHEMBL9787032 0.97 MEN1 (0.73) TSHRMAPK1MEN1KMT2ATHRB
Di(Hydroxyethyl)Ether SCHEMBL1686010 0.96 TSHR (0.77) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL9229031 0.94 MEN1 (0.64) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL5880639 0.94 MEN1 (0.64) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL5339425 0.94 MEN1 (0.64) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL19510384 0.94 MEN1 (0.64) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL5272275 0.94 MEN1 (0.64) TSHRMAPK1MEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7425590-B2 Transparent two phase polyester-polycarbonate compositions EASTMAN CHEMICAL COMPANY (US) 2008-09-16 US claimed
US-20080033088-A1 BLENDS OF POLYESTERS WITH MODIFIED POLYCARBONATES EASTMAN CHEMICAL COMPANY (US) 2008-02-07 US claimed
US-20070015881-A1 Transparent two phase polyester-polycarbonate compositions EASTMAN CHEMICAL COMPANY 2007-01-18 US claimed
US-20060100394-A1 Blends of polyesters with modified polycarbonates EASTMAN CHEMICAL COMPANY 2006-05-11 US claimed
US-7425590-B2 Transparent two phase polyester-polycarbonate compositions EASTMAN CHEMICAL COMPANY (US) 2008-09-16 US disclosed
US-20080033088-A1 BLENDS OF POLYESTERS WITH MODIFIED POLYCARBONATES EASTMAN CHEMICAL COMPANY (US) 2008-02-07 US disclosed
US-20070015881-A1 Transparent two phase polyester-polycarbonate compositions EASTMAN CHEMICAL COMPANY 2007-01-18 US disclosed
US-20060100394-A1 Blends of polyesters with modified polycarbonates EASTMAN CHEMICAL COMPANY 2006-05-11 US disclosed