Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601460 | 0.73 | KDM4E (0.39) | MAPTKDM4EALDH1A1 | |
| SCHEMBL1188799 | 0.72 | JAK2 (0.52) | RPS6KA3ACHEMAPTKDM4EGAA | |
| SCHEMBL2236804 | 0.72 | TYMP (0.52) | RPS6KA3MAPTKDM4EGAASLC22A12 | |
| SCHEMBL11735771 | 0.72 | RPS6KA3 (0.47) | RPS6KA3MAPTKDM4EGAASLC22A12 | |
| SCHEMBL12154908 | 0.72 | TYMP (0.52) | RPS6KA3ACHEMAPTKDM4EGAA | |
| Methane SCHEMBL28724612 | 0.71 | KDM4E (0.38) | MAPTKDM4EALDH1A1 | |
| SCHEMBL8408224 | 0.70 | RPS6KA3 (0.69) | RPS6KA3MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL21941231 | 0.70 | RPS6KA3 (0.69) | RPS6KA3MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL20929164 | 0.69 | SMN1; SMN2 (0.51) | ACHEMAPTKDM4EGAASLC22A12 | |
| SCHEMBL29391661 | 0.69 | RPS6KA3 (0.67) | RPS6KA3MAPTKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12084715-B1 | Methods and systems for reducing artifactual antisense products | 10X GENOMICS, INC. (US) | 2024-09-10 | — | — | US | claimed |
| CN-111235245-B | Method of | 牛津纳米孔科技公开有限公司 | 2024-07-30 | — | — | CN | claimed |
| US-20210332078-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION | Twist Bioscience Corporation | 2021-10-28 | — | — | US | claimed |
| CN-111235245-A | Method of producing a composite material | 牛津纳米孔技术公司 | 2020-06-05 | — | — | CN | claimed |
| EP-3280793-A1 | METHODS FOR DETERMINING BASE LOCATIONS IN A POLYNUCLEOTIDE | The Regents of the University of California (US) | 2018-02-14 | — | — | EP | claimed |
| US-20160333340-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION | Twist Bioscience Corporation | 2016-11-17 | — | — | US | claimed |
| WO-2016183100-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACID AMPLIFICATION | Twist Bioscience Corporation (US) | 2016-11-17 | — | — | WO | claimed |
| WO-2016164363-A1 | METHODS FOR DETERMING BASE LOCATIONS IN A POLYNUCLEOTIDE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-13 | — | — | WO | claimed |
| EP-1419247-B1 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | DIREVO BIOTECH AG (DE) | 2006-09-20 | — | — | EP | claimed |
| EP-1430145-A4 | METHODS AND KITS FOR DETERMING A RISK TO DEVELOP CANCER, FOR EVALUATING AN EFFECTIVENESS AND DOSAGE OF CANCER THERAPY AND FOR CORRELATING BETWEEN AN ACTIVITY OF A DNA REPAIR ENZYME AND A CANCER | YEDA RES & DEV (IL) | 2006-08-16 | — | — | EP | claimed |
| US-20040096863-A1 | Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a dna repair enzyme and a cancer | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-05-20 | — | — | US | claimed |
| EP-1419247-A2 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | Direvo Biotech AG (DE) | 2004-05-19 | — | — | EP | claimed |
| WO-2003012100-A2 | METHOD FOR THE PRODUCTION OF NUCLEIC ACIDS CONSISTING OF STOCHASTICALLY COMBINED PARTS OF SOURCE NUCLEIC ACIDS | DIREVO BIOTECH AG (DE) | 2003-02-13 | — | — | WO | claimed |
| EP-1281757-A1 | Method for the production of nucleic acids consisting of stochastically combined parts of source nucleic acids | Direvo Biotech AG (DE) | 2003-02-05 | — | — | EP | claimed |
| US-20030003454-A1 | Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer | YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE | 2003-01-02 | — | — | US | claimed |
| EP-0949225-B1 | Non-azide gas generating composition | TRW AIRBAG SYS GMBH & CO KG (DE) | 2002-11-20 | — | — | EP | claimed |
| WO-2002076280-A2 | METHODS AND KITS FOR DETERMING A RISK TO DEVELOP CANCER, FOR EVALUATING AN EFFECTIVENESS AND DOSAGE OF CANCER THERAPY AND FOR CORRELATING BETWEEN AN ACTIVITY OF A DNA REPAIR ENZYME AND A CANCER | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2002-10-03 | — | — | WO | claimed |
| US-6132537-A | Azide-free gas-producing composition | TRW AIRBAG SYSTEMS GMBH & CO. KG (DE) | 2000-10-17 | — | — | US | claimed |
| US-5919472-A | DETOXIFYING ALDEHYDE-FIXED BIOLOGICAL TISSUE, SUCH AS HEART VALVE FOR IMPLANTATION BY USING A CYCLIC NONPEPTIDYL AMIDE AND/OR IMIDE FUNCTIONAL COMPOUND SUCH AS ALLANTOIN TO REMOVE EXCESS ALDEHYDE FROM THE TISSUE | MEDTRONIC, INC. (US) | 1999-07-06 | — | — | US | claimed |
| EP-0796627-A2 | Treatment of aldehyde-fixed tissue | MEDTRONIC, INC. (US) | 1997-09-24 | — | — | EP | claimed |