SCHEMBL4817448

SCHEMBL4817448

Cc1c(C)c(N(CC(Cl)(Cl)Cl)C(=O)O)c(C)c2c1OCC2c1ccc(C(C)C)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4814345 0.91
SCHEMBL4818319 0.91
SCHEMBL4819133 0.90
SCHEMBL4819604 0.89 SMN1; SMN2 (0.32)
SCHEMBL4815106 0.88
SCHEMBL4819120 0.85 MAPT (0.32)
SCHEMBL3606931 0.77
SCHEMBL3605777 0.73 SMN1; SMN2 (0.33)
SCHEMBL3596534 0.71 BRD4 (0.33)
SCHEMBL6016029 0.70 POLB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7465815-B2 Cannabinoid receptor modulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-16 US disclosed
US-20070099990-A1 Cannabinoid receptor modulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-05-03 US disclosed