Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.55 |
| ▸ | ABL1 | P00519 | 9/20 | 0.44 |
| ▸ | BCR | P11274 | 9/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720717 | 0.99 | TRPV1 (0.56) | TRPV1ABL1BCRFAAH | |
| SCHEMBL4819485 | 0.91 | TRPV1 (0.47) | TRPV1ABL1BCRFAAH | |
| SCHEMBL4715985 | 0.87 | MAPK10 (0.44) | TRPV1ABL1 | |
| SCHEMBL4819481 | 0.87 | TRPV1 (0.43) | TRPV1ABL1BCRBACE1 | |
| SCHEMBL4716112 | 0.83 | MAPK10 (0.39) | TRPV1 | |
| SCHEMBL4718655 | 0.79 | TRPV1 (0.59) | TRPV1ABL1BCRFAAH | |
| SCHEMBL1013451 | 0.77 | TRPV1 (0.60) | TRPV1ABL1BCRFAAHBACE1 | |
| SCHEMBL13868149 | 0.76 | TRPV1 (0.55) | TRPV1ABL1BCRFAAH | |
| SCHEMBL1013757 | 0.75 | TRPV1 (0.78) | TRPV1ABL1BCRFAAH | |
| SCHEMBL4717536 | 0.75 | TRPV1 (0.61) | TRPV1ABL1BCRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442701-B2 | Amino-heterocycles as VR-1 antagonists for treating pain | MERCK SHARP & DOHME LTD. (GB) | 2008-10-28 | — | — | US | disclosed |
| US-20060040947-A1 | Amino-heterocycles as vr-1 antagonists for treating pain | MERCK SHARP & DOHME LTD. (GB) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040947-A1 | Amino-heterocycles as vr-1 antagonists for treating pain | OPRL1, CNR1, GPR6 | TRPV1 40/4885ABL1 3380/4885BCR 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.