Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.82 |
| ▸ | LCK | P06239 | 17/20 | 0.82 |
| ▸ | MET | P08581 | 16/20 | 0.79 |
| ▸ | TEK | Q02763 | 12/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4548979 | 0.90 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL2746417 | 0.89 | KDR (0.84) | KDRLCKMETTEK | |
| SCHEMBL2748661 | 0.88 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL4548970 | 0.88 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL2747939 | 0.87 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL2748420 | 0.87 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL2747312 | 0.86 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL2747431 | 0.86 | KDR (1.00) | KDRLCKMETTEK | |
| SCHEMBL2747171 | 0.86 | KDR (0.79) | KDRLCKMETTEK | |
| SCHEMBL4548981 | 0.85 | KDR (0.77) | KDRLCKMETTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435823-B2 | Compounds and methods of use | AMGEN INC. (US) | 2008-10-14 | — | — | US | claimed |