Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.89 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL26645800 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL29019843 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL28491845 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL21753520 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL333552 | 1.00 | — | — | |
| Monoethanolamine SCHEMBL29152311 | 0.95 | TSHR (0.80) | TSHRALDH1A1NFKB1 | |
| Monoethanolamine SCHEMBL8935547 | 0.95 | — | — | |
| Monoethanolamine SCHEMBL11769334 | 0.95 | — | — | |
| Monoethanolamine SCHEMBL29152313 | 0.95 | — | — | |
| Monoethanolamine SCHEMBL28170389 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115735919-A | Herbicide composition containing cyclohexane-1, 3-dione derivative and application thereof | 郑州手性药物研究院有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-7396446-B2 | Magnesium anodisation methods | KERONITE INTERNATIONAL LIMITED (GB) | 2008-07-08 | — | — | US | disclosed |
| US-20040238368-A1 | Magnesium anodisation system and methods | KERONITE INTERNATIONAL LIMITED (GB) | 2004-12-02 | — | — | US | disclosed |