⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269 | 1.00 | — | — | |
| SCHEMBL321501 | 1.00 | — | — | |
| SCHEMBL7191672 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL4643957 | 0.95 | — | — | |
| SCHEMBL19897938 | 0.87 | — | — | |
| SCHEMBL7232547 | 0.73 | — | — | |
| SCHEMBL26278 | 0.70 | — | — | |
| SCHEMBL9647703 | 0.70 | — | — | |
| SCHEMBL1361148 | 0.69 | — | — | |
| SCHEMBL2304373 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346858-B1 | METHODS FOR PREPARING OXAZOLIDINONES AND COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME (US) | 2019-08-07 | — | — | EP | claimed |
| WO-2008118935-A1 | COMPOUNDS AND PROCESSES FOR PREPARING SUBSTITUTED AMINOMETHYL-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-E]INDOL-8-ONES | NEUROGEN CORPORATION (US) | 2008-10-02 | — | — | WO | claimed |
| EP-1436258-A4 | PH-DEPENDENT NMDA RECEPTOR ANTAGONISTS | UNIV EMORY (US) | 2005-03-23 | — | — | EP | claimed |
| US-20040138502-A1 | Ph-dependent nmda receptor antagonists | EMORY UNIVERSITY | 2004-07-15 | — | — | US | claimed |
| EP-1436258-A2 | PH-DEPENDENT NMDA RECEPTOR ANTAGONISTS | Emory University (US) | 2004-07-14 | — | — | EP | claimed |
| CN-1134457-C | Novel alpha-aminoacetophenone photoinitiators | BASF | 2004-01-14 | — | — | CN | claimed |
| WO-2002072542-A2 | PH-DEPENDENT NMDA RECEPTOR ANTAGONISTS | EMORY UNIVERSITY (US) | 2002-09-19 | — | — | WO | claimed |
| US-20240190837-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | SYCHRONICITY PHARMA INC (US) | 2024-06-13 | — | — | US | disclosed |
| CN-113480438-B | Preparation method of esmolol hydrochloride | 山东安弘制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240051951-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2024-02-15 | — | — | US | disclosed |
| US-20230416263-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2023-12-28 | — | — | US | disclosed |
| US-11834455-B2 | Carm1 inhibitors and uses thereof | Epizyme, Inc. (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230286965-A1 | BICYCLIC COMPOUND AND USE THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2023-09-14 | — | — | US | disclosed |
| CN-1162312-A | Phenyloxazolidinone antimicrobials | PHARMACIA & UPJOHN CO LLC (US) | 1997-10-15 | — | — | CN | disclosed |
| CN-1160051-A | New substituted oxazolidinones | BAYER AG (DE) | 1997-09-24 | — | — | CN | disclosed |
| US-5412080-A | Enterobactin compounds | PRESIDENT AND FELLOW OF HARVARD COLLEGE (US) | 1995-05-02 | — | — | US | disclosed |
| EP-0445026-B1 | Aminomethylpiperidine derivatives, their process for preparation and the pharmaceutical compositions containing them | ADIR (FR) | 1994-01-26 | — | — | EP | disclosed |
| EP-0445026-A1 | Aminomethylpiperidine derivatives, their process for preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-09-04 | — | — | EP | disclosed |
| US-4045580-A | PHARMACEUTICAL PREPARATION USING 9-(2-HYDROXY-3-AMINO-PROPYL)-9,10-DIHYDRO-9,10-ETHANO-ANTHRACENES AS ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4017542-A | 9-(2-Hydroxy-3-amino-propyl)-9,10-dihydro-9,10-ethano-anthracenes and salts thereof | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |