Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369399 | 0.96 | MC4R (0.43) | MC4RMEN1KMT2ATP53HSD17B10 | |
| SCHEMBL4368944 | 0.94 | MC4R (0.44) | MC4RALDH1A1KDM4ETDP1 | |
| SCHEMBL4823335 | 0.82 | MC4R (0.57) | MC4R | |
| SCHEMBL14027028 | 0.82 | MC4R (0.57) | MC4R | |
| SCHEMBL4816423 | 0.80 | MC4R (0.57) | MC4R | |
| SCHEMBL4146475 | 0.77 | MC4R (0.48) | MC4RKDM4ETDP1 | |
| SCHEMBL16350156 | 0.76 | MC4R (0.47) | MC4R | |
| SCHEMBL4824556 | 0.76 | MC4R (0.49) | MC4RKDM4ETDP1 | |
| SCHEMBL14027017 | 0.76 | KCNH2 (0.57) | MC4R | |
| SCHEMBL4821869 | 0.76 | KCNH2 (0.57) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |