Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 19/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | PTPRA | P18433 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825383 | 0.96 | PTPN1 (0.59) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4825667 | 0.96 | PTPN1 (0.51) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4825770 | 0.96 | PTPN1 (0.51) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4821256 | 0.94 | PTPN1 (0.56) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4823399 | 0.93 | PTPN1 (0.50) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4825860 | 0.91 | PTPN1 (0.54) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4825822 | 0.91 | PTPN1 (0.53) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4826478 | 0.90 | PTPN1 (0.56) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4821226 | 0.90 | PTPN1 (0.49) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4825441 | 0.89 | PTPN1 (0.52) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | claimed |
| EP-1622886-A2 | SUBSTITUTED AMINO CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-08 | — | — | EP | claimed |
| US-20040266789-A1 | Substituted amino carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2004-12-30 | — | — | US | claimed |
| WO-2004099171-A2 | SUBSTITUTED AMINO CARBOXYLIC ACIDS AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE-1B | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
| US-7498356-B2 | Substituted amino carboxylic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498356-B2 | Substituted amino carboxylic acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2009-03-03 | — | — | US | disclosed |
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20040266789-A1 | Substituted amino carboxylic acids | INSTITUTE FOR DIABETES DISCOVERY, L.L.C. | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266789-A1 | Substituted amino carboxylic acids | PTPRS, PPM1B, PTPRO | PTPN1 16/4885PTPRF 11/4885PTPRA 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.