⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28865254 | 0.74 | — | — | |
| SCHEMBL16737080 | 0.74 | — | — | |
| SCHEMBL135584 | 0.74 | — | — | |
| SCHEMBL8542878 | 0.72 | — | — | |
| SCHEMBL9686436 | 0.69 | — | — | |
| SCHEMBL17100057 | 0.67 | — | — | |
| SCHEMBL1526006 | 0.67 | — | — | |
| SCHEMBL11230197 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL2270448 | 0.60 | — | — | |
| SCHEMBL10455480 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427692-B2 | Process for preparation of 7-[α-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid | LUPIN LTD. (US) | 2008-09-23 | — | — | US | disclosed |
| US-7230097-B2 | Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid | LUPIN LTD. (IN) | 2007-06-12 | — | — | US | disclosed |
| US-20060149096-A1 | Process for preparation of 7-[a-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid | LUPIN LTD. (IN) | 2006-07-06 | — | — | US | disclosed |
| US-20050113570-A1 | Process for preparation of 7-[alpha-amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid | LUPIN LTD. (IN) | 2005-05-26 | — | — | US | disclosed |
| US-4504657-A | Cephadroxil monohydrate | BRISTOL-MYERS COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-RE31730-E | Process for the preparation of the crystalline monohydrate of 7-(D-α-aα-(p-hydroxyphenyl)acetamido)-3-methyl-3-cephem-4-carboxylic acid | BRISTOL-MYERS COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| US-4424343-A | Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products | BRISTOL MYERS COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4347354-A | Preparation of 1-N-[ω-amino-α-hydroxyalkanoyl]aminoglycoside polysilylated antibiotics and products obtained therefrom | BRISTOL-MYERS COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4234721-A | Process for the preparation of the crystalline monohydrate of 7-[D-amino-(p-hydroxyphenyl]acetamido)-3-methyl-3-cephen-4-carboxylic acid | BRISTOL-MYERS COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4160863-A | ANTIBIOTIC | BRISTOL-MYERS COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4066657-A | ANTIBACTERIAL AGENTS FOR ANIMAL FEED SUPPLEMENTS | PFIZER INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4036846-A | ANTIBACTERIAL | PFIZER INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-4031077-A | Antibacterial 3-phosphono penams | PFIZER INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-3994939-A | BACTERICIDES | PFIZER INC. (US) | 1976-11-30 | — | — | US | disclosed |