⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14794765 | 1.00 | — | — | |
| SCHEMBL19815793 | 1.00 | — | — | |
| SCHEMBL11659255 | 0.97 | — | — | |
| SCHEMBL28189362 | 0.97 | CYP2D6 (0.33) | — | |
| SCHEMBL2212664 | 0.92 | — | — | |
| SCHEMBL1154203 | 0.92 | — | — | |
| SCHEMBL301967 | 0.92 | — | — | |
| SCHEMBL28317862 | 0.92 | DPP4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6427955 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL1188615 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | claimed |
| US-7348435-B2 | Process for producing cyanopiperidine | JUBILANT ORGANOSYS LIMITED (IN) | 2008-03-25 | — | — | US | claimed |
| US-7291599-B2 | Use of inhibitors of enzymes having activities of amino peptidase N and/or dipeptidyl peptidase IV and of pharmaceutical preparations thereof for a therapy and prevention of chronical neurodegenerative diseases | KEYNEUROTEK AG (DE) | 2007-11-06 | — | — | US | claimed |
| US-7229969-B2 | Combinations of enzyme inhibitors and the use thereof | IMTM GMBH (DE) | 2007-06-12 | — | — | US | claimed |
| US-20070042938-A1 | Use of dpiv and apn inhibitors for the treatment of dermatalogical diseases involving the hyperproliferation and modified differentiation conditions of fibroblasts | IMTM GMBH (DE) | 2007-02-22 | — | — | US | claimed |
| US-20060084808-A1 | Process for producing cyanopiperidine | JUBILANT ORGANOSYS LIMITED (IN) | 2006-04-20 | — | — | US | claimed |
| EP-1289559-B1 | COMBINATIONS OF ENZYME INHIBITOR-CONTAINING PREPARATIONS AND THE USE THEREOF | INST MEDIZINTECHNOLOGIE MAGDEB (DE) | 2005-07-27 | — | — | EP | claimed |
| US-20050014699-A1 | Combinations of enzyme inhibitor-containing preparations and the use thereof | IMTM GMBH (DE) | 2005-01-20 | — | — | US | claimed |
| EP-1487475-A1 | USE OF ENZYME INHIBITORS WITH AMINOPEPTIDASE N AND/OR DIPEPTIDYLPEPTIDASE IV ACTIVITIES AND PHARMACEUTICAL PREPARATIONS PRODUCED THEREFROM FOR THE THERAPY AND PREVENTION OF DERMATOLOGICAL DISEASES WITH SEBORRHOEIC HYPERPROLIFERATION AND ALTERED DIFFERENTIATION STATES | Institut für Medizintechnologie Magdeburg GmbH IMTM. (DE) | 2004-12-22 | — | — | EP | claimed |
| US-20040147434-A1 | Use of enzyme inhibitors of the dipeptidypeptidase iv (ec3.3.14.5) in addition to the aminopeptidase n (ec 3.4.11.2), individually or in a combination thereof, and pharmaceutical preparations thereof for the prevention and/or therapy of ischaemia-caused acute and chronic neurodegenerative process and illnesses, for example | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2004-07-29 | — | — | US | claimed |
| US-20040132639-A1 | Combined use of enzyme inhibitors and pharmaceutical preparations thereof for the treatment and a prophylaxis of arteriosclerosis, for the treatment and prevention of allergic reactions of type I according to the gell and coombs classification and for the treatment and prevention of dermatological diseases associated with fo | IMTM GMBH (DE) | 2004-07-08 | — | — | US | claimed |
| WO-2003077935-A1 | USE OF ENZYME INHIBITORS WITH AMINOPEPTIDASE N AND/OR DIPEPTIDYLPEPTIDASE IV ACTIVITIES AND PHARMACEUTICAL PREPARATIONS PRODUCED THEREFROM FOR THE THERAPY AND PREVENTION OF DERMATOLOGICAL DISEASES WITH SEBORRHOEIC HYPERPROLIFERATION AND ALTERED DIFFERENTIATION STATES | IMTM INSTITUT FÜR MEDIZINTECHNOLOGIE MAGDEBURG GMBH (DE) | 2003-09-25 | — | — | WO | claimed |
| US-20260138961-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4638424-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| CN-119954828-A | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-116322699-B | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2025-02-11 | — | — | CN | disclosed |
| US-4093712-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-06 | — | — | US | disclosed |
| US-4073913-A | INHIBITION AND SUPPRESSION OF THROMBIN | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-02-14 | — | — | US | disclosed |
| US-4072757-A | SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4066773-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-03 | — | — | US | disclosed |