Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.63 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | CASP1 | P29466 | 3/20 | 0.54 |
| ▸ | CASP7 | P55210 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586333 | 0.90 | PIK3CD (0.74) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL14595601 | 0.83 | PIK3CD (0.65) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL22788106 | 0.81 | PIK3CD (0.65) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL30674288 | 0.80 | PIK3CD (0.71) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL2623784 | 0.80 | PIK3CD (0.74) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL15398168 | 0.80 | ALK (0.59) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL24254213 | 0.79 | PIK3CD (0.69) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| Coumarin SCHEMBL7203261 | 0.79 | PIK3CD (0.57) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL12762289 | 0.79 | PIK3CD (0.56) | PIK3CDPIK3CBGLAKDM4EALDH1A1 | |
| SCHEMBL3735216 | 0.79 | PIK3CD (0.65) | PIK3CDPIK3CBGLAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399575-B2 | Laminated photosensitive relief printing original plate and method for producing the relief printing plate | TOKYO OHKA KOGYO CO., LTD. (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20060177771-A1 | Laminated photosensitive relief printing original plate and method for producing the relief printing plate | KODAK AMERICAS LTD. | 2006-08-10 | — | — | US | disclosed |
| WO-2005026836-A2 | LAMINATED PHOTOSENSITIVE RELIEF PRINTING ORIGINAL PLATE AND METHOD FOR PRODUCING THE RELIEF PRINTING PLATE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2005-03-24 | — | — | WO | disclosed |