⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301057 | 1.00 | — | — | |
| SCHEMBL4821291 | 1.00 | — | — | |
| SCHEMBL11571346 | 0.97 | TSHR (0.37) | — | |
| Oxalic Acid SCHEMBL27725531 | 0.94 | TSHR (0.35) | — | |
| SCHEMBL8441834 | 0.87 | TSHR (0.40) | — | |
| Oxalic Acid SCHEMBL5014695 | 0.83 | — | — | |
| Cyclohexene SCHEMBL28564521 | 0.81 | MAPK1 (0.34) | — | |
| SCHEMBL10877511 | 0.76 | MAPK1 (0.31) | — | |
| SCHEMBL7186316 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL1708138 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130196984-A1 | 3-AMINO-5-PHENYL-56-DIHYDRO-2H-[1,4]OXAZINES | SIENA BIOTECH S.P.A. (IT) | 2013-08-01 | — | — | US | disclosed |
| US-20120214806-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINES | ANDREINI MATTEO (IT) | 2012-08-23 | — | — | US | disclosed |
| US-20080262083-A1 | ANTIBACTERIAL AGENTS | IDEXX LABORATORIES, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-7402697-B2 | chloramphenicols; e.g. D-(threo)-1-p-methylsulfonyl-2-amino-3-fluoro-1-propanol(\"Fenicol Compounds\"); antibiotics; veterinary medicine; side effect reducion | IDEXX LABORATORIES INC. (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1836162-A2 | ANTIBACTERIAL AGENTS | IDEXX Laboratories Inc (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2007058639-A2 | ANTIBACTERIAL AGENTS | IDEXX LABORATORIES INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| US-20060047138-A1 | Antibacterial agents | IDEXX LABORATORIES INC. | 2006-03-02 | — | — | US | disclosed |