Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518244 | 0.85 | IL1RN (0.32) | MEN1KMT2A | |
| SCHEMBL22271639 | 0.85 | EP300 (0.37) | PARP1MEN1KMT2ATDP1THRB | |
| SCHEMBL22271503 | 0.85 | TDP1 (0.34) | PARP1TDP1THRBCYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL30915588 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL25297949 | 0.83 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL4825728 | 0.82 | LIMK1 (0.35) | — | |
| SCHEMBL2479269 | 0.75 | CD44 (0.42) | PARP1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL30559712 | 0.75 | CD44 (0.42) | PARP1MEN1KMT2ATDP1CYP3A4 | |
| SCHEMBL21955154 | 0.73 | IL1RN (0.36) | — | |
| SCHEMBL17873234 | 0.73 | KDM4E (0.47) | PARP1ALOX15CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | claimed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | claimed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | KRT18, VIM, CDC73 | PARP1 560/4885MEN1 4089/4885KMT2A 1701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.