Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.59 |
| ▸ | KIFC1 | Q9BW19 | 13/20 | 0.54 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831455 | 0.97 | CDK2 (0.62) | CDK2KIFC1GPR34MMECYP1A2 | |
| SCHEMBL4831769 | 0.95 | CDK2 (0.60) | CDK2KIFC1GPR34MMECYP1A2 | |
| SCHEMBL4829734 | 0.95 | CDK2 (0.56) | CDK2KIFC1GPR34 | |
| SCHEMBL5927451 | 0.95 | CDK2 (0.60) | CDK2KIFC1GPR34MMECYP1A2 | |
| SCHEMBL4831774 | 0.95 | CDK2 (0.60) | CDK2KIFC1GPR34MMECYP1A2 | |
| SCHEMBL5926967 | 0.95 | CDK2 (0.62) | CDK2KIFC1GPR34MME | |
| SCHEMBL5927077 | 0.94 | CDK2 (0.52) | CDK2KIFC1 | |
| SCHEMBL13986710 | 0.94 | CDK2 (0.52) | CDK2KIFC1 | |
| SCHEMBL5926470 | 0.92 | CDK2 (0.57) | CDK2KIFC1 | |
| SCHEMBL5926266 | 0.92 | CDK2 (0.57) | CDK2KIFC1GPR34MMECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459472-B2 | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-7459472-B2 | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-7459472-B2 | Aryl and heteroaryl compounds, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050059713-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | CDK2 1006/4885KIFC1 4489/4885GPR34 4272/4885 |
| US-20050059713-A1 | Aryl and heteroaryl compounds, compositions, and methods of use | CYP2F1, CYP3A43, PNPO | CDK2 456/4885KIFC1 2072/4885GPR34 2331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.