Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | EP300 | Q09472 | 3/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110960 | 0.98 | AKR1C1 (0.65) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28595251 | 0.97 | AKR1C1 (0.62) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL9466663 | 0.95 | AKR1C1 (0.59) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL301985 | 0.91 | MEN1 (0.56) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL29529336 | 0.85 | SLC6A4 (0.54) | AKR1C1SLC6A4SLC6A3CCR2SLC6A2 | |
| SCHEMBL28872387 | 0.85 | SLC6A4 (0.54) | AKR1C1SLC6A4SLC6A3CCR2SLC6A2 | |
| SCHEMBL29886254 | 0.85 | SLC6A4 (0.49) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL28595250 | 0.85 | SLC6A4 (0.49) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL1627025 | 0.84 | MEN1 (0.50) | AKR1C1MEN1KMT2ACCR2AKR1C3 | |
| SCHEMBL11094391 | 0.84 | KCNA3 (0.51) | AKR1C1MEN1KMT2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423067-B2 | N-(3,4-diphenyl-2-butyl)cyclopentancarboxamide derivatives such as N-(2,3-bis(4-chlorophenyl)-1-methylpropyl)-3-benzoyl-cyclopentane-carboxamide; used for treating conditions including psychological disorders, eating disorders and substance abuse | MERCK & CO., INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-20050239828-A1 | Spirocyclic amides as cannabinoid receptor modulators | MERCK & CO., INC. (US) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239828-A1 | Spirocyclic amides as cannabinoid receptor modulators | CNR1, CNR2, MAG | AKR1C1 1581/4885MEN1 238/4885KMT2A 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.