Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.57 |
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831903 | 0.91 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL4822680 | 0.88 | PPARA (0.61) | PPARDPPARAPPARG | |
| SCHEMBL4830371 | 0.88 | PPARA (0.61) | PPARDPPARAPPARG | |
| SCHEMBL4826592 | 0.88 | PPARA (0.61) | PPARDPPARAPPARG | |
| SCHEMBL4828365 | 0.87 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL14017973 | 0.86 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4822468 | 0.85 | PPARD (0.61) | PPARDPPARAPPARG | |
| SCHEMBL4831975 | 0.85 | PPARD (0.61) | PPARDPPARAPPARG | |
| SCHEMBL4822474 | 0.85 | PPARD (0.61) | PPARDPPARAPPARG | |
| SCHEMBL7151194 | 0.84 | PPARD (0.57) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105551-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-12 | — | — | US | claimed |
| US-20040063964-A1 | Thiazole derivatives for treating ppar related disorders | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | claimed |
| EP-1343773-A1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | claimed |
| WO-2002062774-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2002-08-15 | — | — | WO | claimed |
| US-7439259-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439259-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439259-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060276519-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | CADILLA RODOLFO | 2006-12-07 | — | — | US | disclosed |
| US-7105551-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-20040063964-A1 | Thiazole derivatives for treating ppar related disorders | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
| EP-1343773-A1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002062774-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276519-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
| US-20040063964-A1 | Thiazole derivatives for treating ppar related disorders | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.