SCHEMBL482877

SCHEMBL482877

CC=CCc1[c]cccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482794 1.00 MAOB (0.30) MAOB
SCHEMBL9199675 1.00 MAOB (0.30) MAOB
SCHEMBL526546 0.83
SCHEMBL294593 0.82 MAOB (0.33) MAOB
SCHEMBL1069078 0.82 MAOB (0.33) MAOB
SCHEMBL615921 0.80
SCHEMBL1070455 0.80
SCHEMBL3515158 0.79 MAOB (0.30) MAOB
SCHEMBL613044 0.79 TLR8 (0.33) MAOB
SCHEMBL1069057 0.79 TLR8 (0.33) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050154216-A1 Novel enantiomeric compounds for treatment of cardiac arrhythmias and methods of use ARYX THERAPEUTICS 2005-07-14 US claimed
WO-2024143964-A1 CURING AGENT COMPOSITION AND CURABLE COMPOSITION CONTAINING SAME 코오롱인더스트리 주식회사 2024-07-04 WO disclosed
CN-110446739-B Fluoroacetophenone-containing derivative, fluorine-containing additive, curable composition containing the same, and cured product thereof DIC株式会社 2022-01-11 CN disclosed
US-10961405-B2 Fluorine-containing acetophenone derivative, fluroine based additive, curable composition including same, and cured product thereof DIC CORPORATION (JP) 2021-03-30 US disclosed
CN-111954849-A Photosensitive resin composition, cured product, insulating material, resin material for solder resist, and resist member DIC株式会社 2020-11-17 CN disclosed
CN-110446739-A Fluorine-containing acetophenone derivs, fluorine system additive and contain its solidification compound and its solidfied material DAINIPPON INK & CHEMICALS 2019-11-12 CN disclosed
WO-2019198489-A1 PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, INSULATING MATERIAL, RESIN MATERIAL FOR SOLDER RESISTS AND RESIST MEMBER DIC株式会社 2019-10-17 WO disclosed
CN-106414398-B Compound, active energy ray-curable composition, cured product thereof, printing ink, and ink for inkjet recording DIC株式会社 2019-04-05 CN disclosed
EP-1657286-B1 Radiation curable ink jet ink, comprising a polymerisation initiation sensitising dye FUJIFILM CORP (JP) 2018-07-04 EP disclosed
US-9957402-B2 Compound, active energy ray curable composition, cured article thereof, printing ink, and inkjet recording ink DIC CORPORATION (JP) 2018-05-01 US disclosed
CN-1029227-C Composition for denatured denaturation or protection agent for nerve cell and process for preparing benzene derivatives used for composition OTSUKA PHARMA CO LTD (JP) 1995-07-05 CN disclosed
EP-0382213-B1 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMA CO LTD (JP) 1995-05-10 EP disclosed
EP-0609058-A2 Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses SANKYO COMPANY LIMITED (JP) 1994-08-03 EP disclosed
US-5053548-A Containing hydroxy substituents; nervous system disorders OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-01 US disclosed
CN-1044807-A Neurocyte sex change reparation or protective material are with composition and the preparation method that is used for the benzene derivative of said composition OTSUKA PHARMA CO LTD (JP) 1990-08-22 CN disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
US-4282171-A Phosphorus and sulfur containing amides and thioamides THE LUBRIZOL CORPORATION (US) 1981-08-04 US disclosed
US-4208357-A Process for preparing phosphorus and sulfur containing amides and thioamides THE LUBRIZOL CORPORATION (US) 1980-06-17 US disclosed
US-4032461-A PHOSPHORUS AND SULFUR CONTAINING AMIDES AND THIOAMIDES AS LUBRICATING OIL ADDITIVES AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1977-06-28 US disclosed
US-4031023-A Lubricating compositions and methods utilizing hydroxy thioethers THE LUBRIZOL CORPORATION (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154216-A1 Novel enantiomeric compounds for treatment of cardiac arrhythmias and methods of use RYR2, KCNN2, KCNH2 MAOB 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.