Etocarlide

Etocarlide

SCHEMBL4829490

CCOc1ccc(NC(=S)Nc2ccc(OCC)cc2)cc1.[NaH].[SnH2]

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.93
GAA P10253 5/20 0.81
L3MBTL1 Q9Y468 1/20 0.71
ALDH1A1 P00352 8/20 0.66
KDM4E B2RXH2 2/20 0.66
LMNA P02545 5/20 0.65
KMT2A Q03164 5/20 0.62
MEN1 O00255 3/20 0.62
HTT P42858 3/20 0.62
POLB P06746 2/20 0.62
HPGD P15428 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
NSD2 O96028 1/20 0.62
BLM P54132 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
MPI P34949 1/20 0.61
CYP1A2 P05177 1/20 0.61
TDP1 Q9NUW8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etocarlide SCHEMBL676 0.98 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL6508304 0.98 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL2810264 0.98 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL20994029 0.98 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL7343570 0.96 MAPT (0.93) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL9878554 0.96 MAPT (0.93) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL11544997 0.96 MAPT (0.93) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL103618 0.96 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL9263 0.96 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL129915 0.95 MAPT (0.89) MAPTGAAL3MBTL1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-7419527-B2 Increased density particle molding PARTICLE SCIENCES, INC. (US) 2008-09-02 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
WO-2004101200-A2 INCREASED DENSITY PARTICLE MOLDING PARTICLE SCIENCES, INC. (US) 2004-11-25 WO disclosed
US-20040221682-A1 Increased density particle molding PARTICLE SCIENCES, INC. 2004-11-11 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed
EP-1290102-A1 THE USE OF STAR-BRANCHED POLYMERS IN PRESSURE SENSITIVE ADHESIVES National Starch and Chemical Investment Holding Corporation (US) 2003-03-12 EP disclosed
EP-1017746-B1 HYDROPHILIC MATERIALS AND THEIR METHOD OF PREPARATION SUNSMART INC (US) 2002-12-11 EP disclosed
US-6413548-B1 SPHERES; SUSTAINED RELEASE AVEKA, INC. 2002-07-02 US disclosed
WO-2001085138-A2 PARTICULATE ENCAPSULATION OF LIQUID BEADS AVEKA, INC. (US) 2001-11-15 WO disclosed
US-6177540-B1 MERCAPTAN CORE AND THREE OR MORE POLYMER SEGMENTS WHICH EXTEND RADIALLY FROM THE MERCAPTAN CORE INCLUDING CARBOXYLIC ACID MOIETIES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2001-01-23 US disclosed
US-6139613-A Multilayer pigments and their manufacture AVEKA, INC. (US) 2000-10-31 US disclosed
EP-1017746-A1 HYDROPHILIC MATERIALS AND THEIR METHOD OF PREPARATION SUNSMART, INC. (US) 2000-07-12 EP disclosed
US-6045650-A A LIQUID COATING OF AN OXIDIZABLE MATERIAL CONTAINING AT LEAST ONE ELEMENT OTHER THAN CARBON, HYDROGEN, OXYGEN AND NITROGEN IS APPLIED ONTO THE SURFACE OF A SUBSTRATE, OXIDIZING THE OXIDIZABLE MATERIAL TO FORM AN OXIDE COATING SUNSMART, INC. (US) 2000-04-04 US disclosed
US-5962082-A Process for applying liquid coatings to solid particulate substrates AVEKA, INC. (US) 1999-10-05 US disclosed
WO-1999014276-A1 HYDROPHILIC MATERIALS AND THEIR METHOD OF PREPARATION SUNSMART, INC. (US) 1999-03-25 WO disclosed
US-5068291-A Method of preparing pressure sensitive adhesives with accelerated cure rate NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-11-26 US disclosed
US-4292231-A CARBOXY AND CARBAMATE-FUNCTIONAL VINYL INTERPOLYMER ASHLAND OIL, INC. (US) 1981-09-29 US disclosed
US-4005247-A ACRYLATE INTERPOLYMER, METAL ALKOXIDE ASHLAND OIL, INC. (US) 1977-01-25 US disclosed