Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831819 | 0.92 | PPARD (0.78) | PPARDPPARA | |
| SCHEMBL4831713 | 0.91 | PPARD (0.60) | PPARDPPARA | |
| SCHEMBL4831880 | 0.84 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL4822813 | 0.84 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL4826090 | 0.84 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL4830243 | 0.83 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL4830364 | 0.83 | PPARD (0.51) | PPARDPPARA | |
| SCHEMBL4826471 | 0.83 | PPARD (0.51) | PPARDPPARA | |
| SCHEMBL4826476 | 0.83 | PPARD (0.51) | PPARDPPARA | |
| SCHEMBL7101582 | 0.82 | PPARD (0.59) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343773-B1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | SMITHKLINE BEECHAM CORP (US) | 2006-11-02 | — | — | EP | claimed |
| US-7105551-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-12 | — | — | US | claimed |
| US-20040063964-A1 | Thiazole derivatives for treating ppar related disorders | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | claimed |
| EP-1343773-A1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | claimed |
| WO-2002062774-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2002-08-15 | — | — | WO | claimed |
| US-7439259-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439259-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-7439259-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-21 | — | — | US | disclosed |
| US-20060276519-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | CADILLA RODOLFO | 2006-12-07 | — | — | US | disclosed |
| EP-1343773-B1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | SMITHKLINE BEECHAM CORP (US) | 2006-11-02 | — | — | EP | disclosed |
| US-7105551-B2 | Thiazole derivatives for treating PPAR related disorders | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-12 | — | — | US | disclosed |
| US-20040063964-A1 | Thiazole derivatives for treating ppar related disorders | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
| EP-1343773-A1 | THIAZOLE DERIVATIVES FOR TRAEING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002062774-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | GLAXO GROUP LIMITED (GB) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276519-A1 | THIAZOLE DERIVATIVES FOR TREATING PPAR RELATED DISORDERS | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885 |
| US-20040063964-A1 | Thiazole derivatives for treating ppar related disorders | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.