⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137154 | 1.00 | — | — | |
| SCHEMBL102759 | 1.00 | — | — | |
| SCHEMBL5909458 | 0.85 | TSHR (0.73) | — | |
| SCHEMBL10973746 | 0.82 | TSHR (0.67) | — | |
| SCHEMBL10973744 | 0.82 | TSHR (0.67) | — | |
| SCHEMBL13723617 | 0.78 | — | — | |
| SCHEMBL2490273 | 0.78 | — | — | |
| SCHEMBL9678454 | 0.78 | TSHR (0.61) | — | |
| SCHEMBL9121101 | 0.78 | — | — | |
| SCHEMBL1996129 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114605241-B | Preparation method of esketamine hydrochloride intermediate and intermediate thereof | 宜昌人福药业有限责任公司 | 2023-06-02 | — | — | CN | claimed |
| CN-114605241-A | Preparation method of esketamine hydrochloride intermediate and intermediate thereof | 宜昌人福药业有限责任公司 | 2022-06-10 | — | — | CN | claimed |
| WO-2011070459-A1 | PROCESS FOR ENANTIOMERICALLY PURE 8-ARYLOCTANOIC ACIDS AS ALISKIREN | CarboDesign LLC (US) | 2011-06-16 | — | — | WO | claimed |
| EP-4727552-A2 | PASSIVE PERMEABLE PCSK9 ANTAGONIST COMPOUNDS | Merck Sharp & Dohme LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259310-A2 | PASSIVE PERMEABLE PCSK9 ANTAGONIST COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2024-12-19 | — | — | WO | disclosed |
| US-20240400786-A1 | DEPOLYMERIZATION OF POLYURETHANES FOR CIRCULAR ECONOMY PLASTICS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2024-12-05 | — | — | US | disclosed |
| EP-4430064-A1 | CYCLIC PEPTIDE COMPOUNDS WHICH ARE KISS1R RECEPTOR AGONISTS, AND THERAPEUTIC USES THEREOF | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (FR) | 2024-09-18 | — | — | EP | disclosed |
| CN-116804046-B | Cyclic cation antibacterial peptide and application thereof | 科睿铂泰医药科技(深圳)有限责任公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-115382402-B | Preparation method of composite membrane material | 天津工业大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-116804046-A | Cyclic cation antibacterial peptide and application thereof | 科睿铂泰医药科技(深圳)有限责任公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-114605241-B | Preparation method of esketamine hydrochloride intermediate and intermediate thereof | 宜昌人福药业有限责任公司 | 2023-06-02 | — | — | CN | disclosed |
| US-5436334-A | Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-25 | — | — | US | disclosed |
| US-5277895-A | Nuclear magnetic resonance | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| EP-0551653-A1 | Enantiomeric pure 2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |
| EP-0485045-A2 | Mono-N-substituted 1,4,7,10-Tetraazacyclododecan-derivatives, process for their preparation and pharmaceutical agent containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0270006-B1 | EFFICIENT CIS-TO-TRANS ISOMERIZATION OF 1, 4-DIHALOBUTENE-2 | HENKEL CORPORATION (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0270006-A1 | Efficient cis-to-trans isomerization of 1, 4-dihalobutene-2 | HENKEL CORPORATION (US) | 1988-06-08 | — | — | EP | disclosed |
| US-4306100-A | Process for production of alkenediols | STANDARD OIL COMPANY (INDIANA) (US) | 1981-12-15 | — | — | US | disclosed |
| US-3978080-A | ANTIINFLAMMATORY, HYPOLIPIDEMIC | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |
| US-3960874-A | ANTIINFLAMMATORY, HYPOLIPIDEMIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |