Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 5/20 | 0.78 |
| ▸ | PIM1 | P11309 | 5/20 | 0.73 |
| ▸ | RET | P07949 | 10/20 | 0.64 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331910 | 0.88 | FYN (0.78) | FYNPIM1RETPIM2 | |
| SCHEMBL4326933 | 0.88 | FYN (0.78) | FYNPIM1RETPIM2 | |
| SCHEMBL30521824 | 0.88 | FYN (1.00) | FYNPIM1RETPIM2 | |
| SCHEMBL14302654 | 0.88 | FYN (0.78) | FYNPIM1RETPIM2 | |
| SCHEMBL4594923 | 0.88 | FYN (0.78) | FYNPIM1RETPIM2 | |
| SCHEMBL4594270 | 0.88 | FYN (1.00) | FYNPIM1RETPIM2 | |
| SCHEMBL4338192 | 0.88 | FYN (0.78) | FYNPIM1RETPIM2 | |
| SCHEMBL4342469 | 0.87 | FYN (0.76) | FYNPIM1RETPIM2 | |
| SCHEMBL4340688 | 0.87 | RET (0.79) | FYNPIM1RETPIM2 | |
| SCHEMBL4340337 | 0.85 | FYN (0.74) | FYNPIM1RETPIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |