Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838067 | 1.00 | FOLH1 (0.49) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL4840201 | 0.86 | PPARA (0.46) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL4833172 | 0.86 | PPARA (0.46) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL27498880 | 0.85 | SLC1A1 (0.46) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL2252306 | 0.84 | CYP2C19 (0.46) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL7242407 | 0.83 | KMT2A (0.50) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL7233601 | 0.83 | KMT2A (0.50) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL27757633 | 0.83 | KMT2A (0.50) | FOLH1SLC1A1CA1CA2CA7 | |
| SCHEMBL22086824 | 0.81 | HTT (0.46) | FOLH1SLC1A1KMT2ACYP2C19HTT | |
| SCHEMBL8722230 | 0.80 | CYP2C19 (0.47) | FOLH1SLC1A1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7468448-B2 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
| US-20050256322-A1 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1589018-A1 | PROCESS FOR PRODUCING HEXAHYDROFUROFURANOL DERIVATIVE, INTERMEDIATE THEREOF AND PROCESS FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-10-26 | — | — | EP | disclosed |
| US-6867321-B2 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20040162340-A1 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256322-A1 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | CYP4F11, CYP51A1, CYP4A11 | FOLH1 1990/4885SLC1A1 4828/4885CA1 3918/4885 |
| US-20040162340-A1 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof | CYP4F11, CYP51A1, CYP4A11 | FOLH1 1979/4885SLC1A1 4827/4885CA1 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.