SCHEMBL4833010

SCHEMBL4833010

CCCCCC(C)(C#N)N=NC(C)(C#N)CCCCC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
THRB P10828 1/20 0.30
GGPS1 O95749 2/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095641 1.00 TSHR (0.33) TSHRTHRBGGPS1FDPS
SCHEMBL7095037 0.98 TSHR (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL11761827 0.98 TSHR (0.32) TSHR
SCHEMBL7095039 0.98 TSHR (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL7781967 0.98 TSHR (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL11761822 0.98 TSHR (0.32) TSHR
SCHEMBL7781965 0.98 TSHR (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL3061988 0.98 TSHR (0.35) TSHRTHRBGGPS1FDPS
SCHEMBL11763639 0.96 TSHR (0.33) TSHRTHRBGGPS1FDPS
SCHEMBL7098197 0.96 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11865374-B2 Functionalized polymers EVONIK OPERATIONS GMBH (DE) 2024-01-09 US claimed
US-20230312791-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2023-10-05 US claimed
EP-4200343-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2023-06-28 EP claimed
CN-116096764-A Functionalized polymers 赢创运营有限公司 2023-05-09 CN claimed
WO-2022038054-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-02-24 WO claimed
EP-3957659-A1 FUNCTIONALIZED POLYMERS Evonik Operations GmbH (DE) 2022-02-23 EP claimed
EP-3710503-B1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2022-01-05 EP claimed
US-20200383896-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2020-12-10 US claimed
EP-3710503-A1 FUNCTIONALIZED POLYMERS Evonik Degussa GmbH (DE) 2020-09-23 EP claimed
WO-2006110305-A1 PHOTOCHROMIC OPHTHALMIC DEVICES MADE WITH DUAL INITIATOR SYSTEM JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-10-19 WO claimed
US-20060227287-A1 Photochromic ophthalmic devices made with dual initiator system MOLOCK FRANK 2006-10-12 US claimed
US-20030195311-A1 Multi-component liquid azo-peroxide initiator mixture and method for using same CROMPTON CORPORATION 2003-10-16 US claimed
EP-0847383-B1 MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES DU PONT (US) 2001-11-07 EP claimed
US-5760192-A FREE RADICAL, POLYMERIZATION CATALYSTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-02 US claimed
US-4061590-A Catalyst composition of an azo nitrile mixture in an organic solvent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-06 US claimed
US-3987025-A POLYMERIZATION INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-10-19 US claimed
US-11865374-B2 Functionalized polymers EVONIK OPERATIONS GMBH (DE) 2024-01-09 US disclosed
US-20230312791-A1 FUNCTIONALIZED POLYMERS EVONIK OPERATIONS GMBH (DE) 2023-10-05 US disclosed
US-3970612-A BULK POLYMERIZATION HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-07-20 US disclosed
US-3948740-A Polymerization of water soluble monomers with radiation and chemical initiator HERCULES INCORPORATED (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11865374-B2 Functionalized polymers PUF60, PARN, PARG TSHR 2538/4885THRB 3767/4885GGPS1 3154/4885
US-20200383896-A1 FUNCTIONALIZED POLYMERS PUF60, PARN, PARG TSHR 2538/4885THRB 3767/4885GGPS1 3154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.