⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15836240 | 1.00 | CA12 (0.58) | — | |
| SCHEMBL17780256 | 0.89 | CA12 (0.48) | — | |
| SCHEMBL5586365 | 0.89 | CA12 (0.48) | — | |
| SCHEMBL8263013 | 0.89 | CA12 (0.48) | — | |
| SCHEMBL15214569 | 0.89 | CA12 (0.48) | — | |
| SCHEMBL12820397 | 0.89 | CA12 (0.48) | — | |
| SCHEMBL14922462 | 0.89 | CA12 (0.48) | — | |
| SCHEMBL1679214 | 0.88 | CA12 (0.59) | — | |
| SCHEMBL1434773 | 0.88 | — | — | |
| SCHEMBL12018141 | 0.87 | CA12 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355012-A | Novel heterocyclic substituted pyrimidine derivative exhibiting cancer cell growth inhibitory effect and pharmaceutical composition containing the same | 昂科比克斯有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-113831302-A | Benzisoselenazolone derivative and preparation method and application thereof | 山东大学 | 2021-12-24 | — | — | CN | claimed |
| US-20120301426-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-11-29 | — | — | US | claimed |
| EP-2440519-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-04-18 | — | — | EP | claimed |
| WO-2010144371-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INIHIBITOR COMPOUNDS | GILEAD COLORADO, INC. (US) | 2010-12-16 | — | — | WO | claimed |
| US-20100310500-A1 | ALKANOYLAMINO BENZAMIDE ANILINE HDAC INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-12-09 | — | — | US | claimed |
| CN-1832929-A | 2, 4-pyrimidinediamines for the treatment of neoplastic diseases, inflammatory diseases and immune system disorders | NOVARTIS AG (CH) | 2006-09-13 | — | — | CN | claimed |
| WO-2024253476-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BRAIN TUMOR | 주식회사 에스트리온 | 2024-12-12 | — | — | WO | disclosed |
| WO-2024253475-A1 | NOVEL COMPOUND AND PREPARATION METHOD THEREFOR | 주식회사 에스트리온 | 2024-12-12 | — | — | WO | disclosed |
| CN-118355012-A | Novel heterocyclic substituted pyrimidine derivative exhibiting cancer cell growth inhibitory effect and pharmaceutical composition containing the same | 昂科比克斯有限公司 | 2024-07-16 | — | — | CN | disclosed |
| WO-2024105363-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024094171-A1 | SUBSTITUTED AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2024-05-10 | — | — | WO | disclosed |
| WO-2024017251-A1 | MACROCYCLE FOR INHIBITING AND INDUCING EGFR DEGRADATION AND PREPARATION METHOD FOR AND USE OF MACROCYCLE | 江苏恒瑞医药股份有限公司 | 2024-01-25 | — | — | WO | disclosed |
| CN-1788001-A | 2, 4-bis (phenylamino) pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders | NOVARTIS AG (CH) | 2006-06-14 | — | — | CN | disclosed |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | SANKYO AGRO COMPANY, LIMITED (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1426365-A1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | Sankyo Agro Company, Limited (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-1337550-A2 | HEPATITIS C TRIPEPTIDE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002060926-A2 | HEPATITIS C TRIPEPTIDE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |