Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065423 | 1.00 | NTRK1 (0.80) | NTRK1IGF1R | |
| SCHEMBL4640146 | 0.94 | NTRK1 (0.73) | NTRK1IGF1R | |
| SCHEMBL23216996 | 0.91 | NTRK1 (0.83) | NTRK1IGF1R | |
| SCHEMBL3342109 | 0.91 | NTRK1 (0.83) | NTRK1IGF1R | |
| SCHEMBL4144533 | 0.89 | NTRK1 (0.83) | NTRK1IGF1R | |
| SCHEMBL4144068 | 0.89 | NTRK1 (1.00) | NTRK1IGF1R | |
| SCHEMBL4147228 | 0.89 | NTRK1 (1.00) | NTRK1IGF1R | |
| SCHEMBL4144674 | 0.89 | NTRK1 (1.00) | NTRK1IGF1R | |
| SCHEMBL4160280 | 0.89 | NTRK1 (0.83) | NTRK1IGF1R | |
| SCHEMBL4072344 | 0.89 | NTRK1 (0.80) | NTRK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877057-A1 | USE OF PYRAZOLYL-PYRIMIDINE DERIVATIVES IN THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006115452-A1 | USE OF PYRAZOLYL-PYRIMIDINE DERIVATIVES IN THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | WO | disclosed |