⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832799 | 0.88 | USP7 (0.48) | — | |
| SCHEMBL14064428 | 0.87 | MAPK11 (0.50) | — | |
| SCHEMBL4839254 | 0.87 | — | — | |
| SCHEMBL3121232 | 0.86 | — | — | |
| SCHEMBL14064448 | 0.86 | — | — | |
| SCHEMBL4838123 | 0.85 | — | — | |
| SCHEMBL14064441 | 0.84 | — | — | |
| SCHEMBL4832531 | 0.84 | — | — | |
| SCHEMBL4829651 | 0.84 | — | — | |
| SCHEMBL4836747 | 0.80 | TRPC3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429590-B2 | Antiprotozoal imidazopyridine compounds | MERCK & CO. INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429590-B2 | Antiprotozoal imidazopyridine compounds | MERCK & CO. INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429590-B2 | Antiprotozoal imidazopyridine compounds | MERCK & CO. INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-20060293303-A1 | Antiprotozoal imidazopyridine compounds | MERCK SHARP & DOHME LLC | 2006-12-28 | — | — | US | disclosed |