Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1649790 | 0.92 | EPAS1 (0.35) | EPAS1AKR1B1 | |
| SCHEMBL4835933 | 0.90 | EPAS1 (0.33) | EPAS1 | |
| SCHEMBL1651357 | 0.82 | KMT2A (0.35) | EPAS1AKR1B1 | |
| SCHEMBL1649788 | 0.80 | EPAS1 (0.38) | EPAS1 | |
| SCHEMBL1653517 | 0.79 | EPAS1 (0.36) | EPAS1AKR1B1 | |
| SCHEMBL1651526 | 0.79 | EPAS1 (0.37) | EPAS1 | |
| SCHEMBL1651017 | 0.79 | GAA (0.36) | EPAS1 | |
| SCHEMBL585881 | 0.77 | EPAS1 (0.42) | EPAS1 | |
| SCHEMBL1650552 | 0.76 | EPAS1 (0.37) | EPAS1 | |
| SCHEMBL1651101 | 0.75 | PTGDR2 (0.39) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963259-A2 | SUBSTITUTED DIPHENYLETHERS, -AMINES, -SULFIDES AND -METHANES FOR THE TREATMENT OF RESPIRATORY DISEASE | AstraZeneca AB (SE) | 2008-09-03 | — | — | EP | claimed |
| WO-2007068894-A2 | SUBSTITUTED DIPHENYLETHERS, -AMINES, -SULFIDES AND -METHANES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |