⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23109060 | 1.00 | — | — | |
| SCHEMBL28762257 | 0.79 | — | — | |
| SCHEMBL6023550 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL30084769 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL17655237 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28783865 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL31255671 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL1129844 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL28564370 | 0.70 | KDM4E (0.33) | — | |
| SCHEMBL22138536 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101676-A1 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-12 | — | — | US | claimed |
| WO-2005014524-A2 | AMINO THIOL COMPOUNDS AND COMPOSITIONS FOR USE IN CONJUNCTION WITH CANCER THERAPY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-02-17 | — | — | WO | claimed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-20050101676-A1 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-12 | — | — | US | disclosed |
| WO-2005014524-A2 | AMINO THIOL COMPOUNDS AND COMPOSITIONS FOR USE IN CONJUNCTION WITH CANCER THERAPY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2005-02-17 | — | — | WO | disclosed |
| EP-0133097-B1 | SYNERGISTIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | RHONE-POULENC SANTE (FR) | 1987-03-04 | — | — | EP | disclosed |
| EP-0133098-B1 | SYNERGISTIN DERIVATIVES AND THEIR PREPARATION | RHONE-POULENC SANTE (FR) | 1987-01-14 | — | — | EP | disclosed |
| EP-0133097-A1 | Synergistin derivatives, their preparation and pharmaceutical compositions thereof | RHONE-POULENC SANTE (FR) | 1985-02-13 | — | — | EP | disclosed |
| EP-0133098-A1 | Synergistin derivatives and their preparation | RHONE-POULENC SANTE (FR) | 1985-02-13 | — | — | EP | disclosed |