Sugi Predict

Sugi Predict / Compounds / SCHEMBL483615

SCHEMBL483615

SCHEMBL483615

c1ccc(-c2ccc3c(c2)oc2ccccc23)nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 3/20 0.47
▸ MAPT P10636 6/20 0.46
▸ HPGD P15428 6/20 0.46
▸ KDM4E B2RXH2 6/20 0.46
▸ ALDH1A1 P00352 5/20 0.46
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ NPC1 O15118 3/20 0.45
▸ HSD17B10 Q99714 4/20 0.44
▸ CYP1A2 P05177 3/20 0.44
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ RAB9A P51151 3/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ HCRTR1 O43613 1/20 0.43
▸ LMNA P02545 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ CCR1 P32246 1/20 0.42
▸ CCR5 P51681 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30531496 1.00 AHR (0.47) AHRMAPTHPGDKDM4EALDH1A1
SCHEMBL21019565 0.92 AHR (0.44) AHRMAPTHPGDKDM4EALDH1A1
SCHEMBL17472509 0.91 HCRTR1 (0.54) AHRMAPTHPGDKDM4EALDH1A1
SCHEMBL17486247 0.90 NPC1 (0.53) AHRMAPTHPGDKDM4EALDH1A1
SCHEMBL21019348 0.86 AHR (0.42) AHRMAPTHPGDKDM4EALDH1A1
SCHEMBL15696765 0.86 CYP2A6 (0.45) MAPTHPGDKDM4EALDH1A1NPC1
SCHEMBL23542943 0.86 DHODH (0.43) AHRMAPTHPGDKDM4EALDH1A1
SCHEMBL15696837 0.86 KDM4E (0.46) AHRHPGDKDM4EALDH1A1NPC1
SCHEMBL15696775 0.86 PRMT5 (0.41) AHRHPGDKDM4EALDH1A1MEN1
SCHEMBL15696773 0.86 CYP2A6 (0.47) MAPTHPGDKDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 — — EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 — — US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 — — EP disclosed
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-05-30 — — US disclosed
US-11910701-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 — — US disclosed
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 — — US disclosed
CN-112028941-B Heteroleptic iridium complexes 通用显示公司 2023-08-29 — — CN disclosed
US-11637251-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 — — US disclosed
US-11637251-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 — — US disclosed
US-20140203268-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2014-07-24 — — US disclosed
US-8722205-B2 Heteroleptic iridium complex UNIVERSAL DISPLAY CORPORATION (US) 2014-05-13 — — US disclosed
US-8722205-B2 Heteroleptic iridium complex UNIVERSAL DISPLAY CORPORATION (US) 2014-05-13 — — US disclosed
US-8722205-B2 Heteroleptic iridium complex UNIVERSAL DISPLAY CORPORATION (US) 2014-05-13 — — US disclosed
EP-2411401-A1 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2012-02-01 — — EP disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — US disclosed
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — US disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — WO disclosed
WO-2010111175-A1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORPORATION (US) 2010-09-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11910701-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 AHR 1612/4885MAPT 910/4885HPGD 2170/4885
US-20240180020-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 AHR 1612/4885MAPT 910/4885HPGD 2170/4885
US-11637251-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 AHR 1612/4885MAPT 910/4885HPGD 2170/4885
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 AHR 1612/4885MAPT 910/4885HPGD 2170/4885
US-20100244004-A1 HETEROLEPTIC IRIDIUM COMPLEX DDT, ICOSLG, PDCD1LG2 AHR 625/4885MAPT 744/4885HPGD 2166/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 AHR 794/4885MAPT 1607/4885HPGD 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.