Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782084 | 0.78 | SMN1; SMN2 (0.49) | MAPTLMNASMN1; SMN2TP53MEN1 | |
| SCHEMBL4780046 | 0.77 | TSHR (0.46) | MAPTLMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL4777271 | 0.69 | ROCK1 (0.48) | LMNASMN1; SMN2 | |
| SCHEMBL4865927 | 0.69 | SMN1; SMN2 (0.63) | MAPTLMNASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4726471 | 0.69 | ROCK1 (0.47) | LMNA | |
| SCHEMBL4725491 | 0.69 | ROCK1 (0.47) | LMNA | |
| SCHEMBL4777278 | 0.69 | ROCK1 (0.44) | LMNASMN1; SMN2 | |
| SCHEMBL4726466 | 0.68 | ROCK1 (0.49) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL4959287 | 0.67 | MAPK1 (0.56) | MAPTLMNASMN1; SMN2TP53MEN1 | |
| SCHEMBL4727100 | 0.67 | ROCK1 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011191-A1 | ANTIBACTERIAL HETEROCYCLIC UREAS | REPLIDYNE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |